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Juniper Publishers - Surviving Major Trauma with Hemipelvectomy - Journal of Anesthesia & Intensive Care Medicine (JAICM)

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Juniper Publishers - Open Access Journal of Journal of Anesthesia & Intensive Care Medicine Surviving Major Trauma with Hemipelvectomy Authored by  Christina Müller-Höcker Traumatic hemipelvectomy is a life threatening, however rare injury associated with high lethality. It comes along with excessive blood loss, related hemodynamic instability and injuries of the genitor-urinary system or the rectum. The real incidence is unknown because most patients die before reaching the hospital. The treatment requires a rapid, multidisciplinary team approach focused on hemorrhage control to correct coagulopathy and clear persistent signs of tissue hypoperfusion to save the patient’s life [1]. Improvements in prehospital rescue systems and initial trauma response have resulted in increased chances of survival. Most survivors are young, healthy individuals, who are able to tolerate massive hemorrhage and soft-tissue destruction [2-6]. We present a case

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Idiopathic Hyperammonemia after Orthotopic Lung Transplantation - Juniper Publishers - Journal of Anesthesia & Intensive Care Medicine

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Juniper Publishers - Open Access Journal of  Journal of Anesthesia & Intensive Care Medicine Idiopathic Hyperammonemia after Orthotopic Lung Transplantation Authored by  Tyson Kathleen Idiopathic hyperammonemia is characterized by increased serum ammonia levels (>200umol/L) and is sometimes associated with normal to slightly elevated liver function tests [1]. These patients often present with encephalopathy, cerebral edema, seizures, and coma. Idiopathic hyperammonemia has been reported after high dose chemotherapy, and organ transplants including Orthotopic lung transplant [2]. Hyperammonemia is a rare, severe, and often fatal complication. There are few cases reported in the literature since 1997, including one retrospective analysis of 807 lung transplants; only 8 patients were diagnosed with hyperammonemia [3]. The exact mechanism of idiopathic hyperammonemiais not fully understood with congenital or acquired defects in ammonia metabolism, as well a