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Dexmedetomidine V/S Fentanyl with 0.75% Ropivacaine for Epidural Anaesthesia in Lower Abdominal Surgeries - A Comparative Study-Juniper Publishers

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Juniper Publishers - Journal of Anesthesia Abstract Background: Opioids as epidural adjunct to local anaesthetics have been in use since long and a-2 agonists are being increasingly used for similar purpose. This study was done to compare the effects of epidurally administered dexmedetomidine and fentanyl in combination with Ropivacaine 0.75% in lower abdominal surgeries. Methods: 80 patients of either sex, aged 18-55 years, ASA grade I-II posted for elective lower abdominal surgery were divided into two groups (n=40) by open label randomization chit method. Group RD received 1^g/kg Dexmedetomidine and group RF received 1^g/kg Fentanyl along with 15 ml Ropivacaine 0.75%. Onset and time of complete sensory and motor blockade, two segmental dermatomal regression, duration of analgesia, first 24 hour total LA consumption and complications were recorded. Data were compiled and analysed using Chi-square test and Fisher's exact test. Results: Onset of complete...