Comparitive Study of Bupivacaine with Nalbuphine and Bupivacaine alone for Post-Operative Analgesia in Subarachnoid Block for Lower Limb Surgeries- Prospective Randomised Study-Juniper Publishers
Juniper Publishers - Journal of Anesthesia Abstract Background: Nalbuphine is a synthetic opioid , with kappa agonist or partial µ antagonist action. When added as an adjuvant to intrathecal bupivacaine, it acts on dorsal horn of spinal cord producing analgesia with decreased incidence of µ receptor side effects. Aims and Objectives: To compare the onset, duration of sensory blockade, duration of motor blockade, 2 segment regression and duration of post operative analgesia achieved, by comparing hyperbaric bupivacaine alone with hyperbaric bupivacaine and nalbuphine after intrathecal administration. Material and Methods: Randomised double blind study done on 60 patients, who were undergoing lower limb surgeries under subarachnoid block. Patients were divided into two groups, group B receiving 15mg of 0.5% hyperbaric bupivacaine+0.1ml of normal saline and group N receiving 15mg of hyperbaric bupivacaine+0.1ml of nalbuphine (1mg). Assessment of duration of motor ...