Juniper Publishers Journal of Anesthesia and Intensive Care Medicine

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Juniper Publishers - Open Access Journal of Journal of Anesthesia & Intensive Care Medicine Monitoring the Depth of Anesthesia and Current Technology Authored by  Daniel Alfonso Botero-Rosas General anesthesia (GA) is defined as a drug-induced loss of consciousness during which patients are not arousable, even by painful stimulation [ 1 ]. GA takes an important role in surgical procedures where an anesthetic overdose may lead to drug-associated toxicities, coma and even death; on the other hand a light anesthetic dose may lead to the well-known event of intraoperative awareness, which can cause sleep disorders, depression, night terrors, hospitals fears and post-traumatic stress disorder [ 2 - 4 ]. In this context, monitoring depth of anesthesia has become an important issue in anesthesiology. Electroencephalographic signal (EEG) reflects the activity of the central nervous system and it has been widely used for monitoring depth of anesthesia. In ge...

Juniper Publishers - Open Access Journals Multimodal Anesthesia for Glaucoma Surgery in a Child with Mitochondrial Disease and Malignant Hyperthermia Authored by Benjamin Pruden Mitochondrial diseases (MD) are characterized by impairments of mitochondrial function that precipitate metabolic acidosis. An 8-year-old MD female with prior anesthesia exposure complicated by metabolic acidosis, seizures and propofol infusion syndrome, presented for glaucoma surgery. We present a multimodal balanced anesthetic technique used to successfully manage this complex case. Mitochondrial disorders (MD) are a heterogeneous group of genetic disorders that impair mitochondrial integrity and result in deficient energy production. The disorder has an incidence of 1:5000 live births [1], and affects tissues with high-energy requirements such as the central nervous system, retina, heart and muscle [2]. Consequently, these patients have multiple co-morbidities that include cardiac...

Juniper Publishers - Open Access Journals Multimodal Anesthesia for Glaucoma Surgery in a Child with Mitochondrial Disease and Malignant Hyperthermia Authored by Benjamin Pruden Mitochondrial diseases (MD) are characterized by impairments of mitochondrial function that precipitate metabolic acidosis. An 8-year-old MD female with prior anesthesia exposure complicated by metabolic acidosis, seizures and propofol infusion syndrome, presented for glaucoma surgery. We present a multi modal balanced anesthetic technique used to successfully manage this complex case. To view Full Text in our Journal of Anesthesia & Intensive Care Medicine           

Using Ultrasound to Confirm Endotracheal Tube Position in the Intensive Care Unit  Authored by  Ahmad Alwassia This was a prospectively designed study. Eligible patients were 18 years or older, that were admitted to the medical intensive care unit, that required endotracheal intubation due to their underlying clinical condition. An immediate post intubation Ultrasound examination was performed by an intensivist, who was not involved in clinical management of the patient and was blinded to the result of the standard confirmatory methods of endotracheal tube placement. The clinician performing the intubation was blinded to the results of the ultrasound examination findings. To read more Full text in Juniper Publishers   

Focusing on Fundamentals   Authored by Amballur David John In a time of rapid knowledge expansion, technological innovation, emphasis on cost containment and improving efficiency in delivering medical care, it is easy to overlook the fundamentals of medicine. The sudden onset of new diseases, such as the Ebola virus which can cause rapid spread, panic, multisystem failure, and death or the Zika virus which is spread by an abundant common factor the mosquito, and which can cause catastrophic developmental anomalies to pregnant women resulting in children who will bear the consequences of these defects for a life time; emphasizes the importance of acquiring and spreading information, quickly. To view more Full Text in Juniper Publishers

Current State of Pharmacodynamic Target Attainment in Critically Ill Patients with Severe Sepsis in Canadian Icus: Prospective Cohort Study Authored by Clarence Chant In this multicenter observational study, adult Canadian ICU patients with severe sepsis were prospectively followed. The minimum inhibitory concentration (MIC) of the organism was obtained from hospital’s microbiology laboratory, and pharmacodynamic targets (PD) of the prescribed empiric antibiotics were calculated using population pharmacokinetic parameters to estimate the rate of PD target attainment. To view more Fulltext in Juniper Publishers

The Effect on Overall Cost and Health-Related Quality of Life by Inpatient Trajectories 3 Years Before and After Critical Illness Authored by   Lotti Orwelius Pre-existing disease is the most important factor in the prediction of health-related quality of life (HRQoL) after intensive care. We hypothesised that the “inpatient care trajectories” in the years before admission to the ICU is a stronger predictor of HRQoL and mortality after intensive care than pre-existing disease, and that it has significant effects on overall costs. To view more FullText in Juniper Publishers

Effect of A Slow Ramp Rate on Exercise Testing: A Healthy Volunteer Study Authored by Julian Martin Brown Ramp rates for incremental ramp rate exercise testing are not standardised. The ramp rate may influence the values obtained during exercise testing. We compared a slow ramp rate (SR) (3watts/minute) to a fast ramp rate (FR) (20 watts/minute) in 8 fit non elite cyclists using cycle ergometry. We measured peak power ,oxygen consumption (VO2) at anaerobic threshold (AT) and maximum aerobic capacity (VO2 max). A lower mean peak work (369 Watts vs 406 watts, P=0.004), higher mean AT (42.1 ml/min/kg vs 38.6 ml/min/kg, p=0.16) , lower mean VO2 max (51.7 ml/min/kg vs 54 ml/min/kg p=0.25) and higher ratio of AT to VO2 max (0.82 vs 0.71 p = 0.03) were obtained using the SR protocol. To view more FullText in JuniperPublishers