Current State of Pharmacodynamic Target Attainment in Critically Ill Patients with Severe Sepsis in Canadian Icus: Prospective Cohort Study


Authored by Clarence Chant

In this multicenter observational study, adult Canadian ICU patients with severe sepsis were prospectively followed. The minimum inhibitory concentration (MIC) of the organism was obtained from hospital’s microbiology laboratory, and pharmacodynamic targets (PD) of the prescribed empiric antibiotics were calculated using population pharmacokinetic parameters to estimate the rate of PD target attainment.

To view more Fulltext in Juniper Publishers

Comments

Post a Comment

Popular posts from this blog

Total Spinal Blockage after Spinal Anaesthesia for Perianal Fistula-Juniper Publishers

Juniper Publishers - Journal of Anesthesia Abstract Total spinal block is one of the rare complications of regional anaesthesia. It can occur after spinal, epidural or nerve plexus block. Early detection and treatment is essential to prevent mortality. We report a case of total spinal block occurring in a man with perianal fistula after receiving uneventful spinal anaesthesia for caesarean section treated successfully with prompt cardiovascular resuscitation and general anaesthesia. Introduction Spinal anaesthesia is being increasing used as a mode of anaesthesia for performing treatment for perianal fistula [ 1 ]. Although it is a safe and effective means of giving anaesthesia, at times it can lead to complications like hypotension, shivering, respiratory distress, unconsciousness, etc [ 2 ]. Total spinal block is a rare complication of spinal anaesthesia. It is a life threatening complication presenting with symptoms of
Read more