Multimodal Anesthesia for Glaucoma Surgery in a Child with Mitochondrial Disease and Malignant Hyperthermia - Juniper Publishers - Journal of Anesthesia & Intensive Care Medicine
Juniper Publishers - Open Access Journals
Multimodal Anesthesia for Glaucoma Surgery in a Child with Mitochondrial Disease and Malignant Hyperthermia
Authored by Benjamin Pruden
Mitochondrial diseases (MD) are characterized by impairments of
mitochondrial function that precipitate metabolic acidosis. An
8-year-old MD female with prior anesthesia exposure complicated by
metabolic acidosis, seizures and propofol infusion syndrome, presented
for glaucoma surgery. We present a multimodal balanced anesthetic
technique used to successfully manage this complex case.
Mitochondrial disorders (MD) are a heterogeneous group of genetic
disorders that impair mitochondrial integrity and result in deficient
energy production. The disorder has an incidence of 1:5000 live births
[1], and affects tissues with high-energy requirements such as the
central nervous system, retina, heart and muscle [2]. Consequently,
these patients have multiple co-morbidities that include cardiac,
endocrine, and neurologic dysfunction [3-5]. Current evidence suggests
that mitochondrial disease may be a contributing factor in the
pathogenesis of glaucoma [6]. Anesthesia in this patient population may
prove hazardous because the stress of surgery and fasting can induce
marked metabolic aberrations, most commonly lactic acidosis [7].
For more articles in Journal of clinical anesthesia research please click on https://juniperpublishers.com/jaicm/index.php
To read more Open Access Journal of Anesthesia
To read more…FullText in Juniper Publishers Click on https://juniperpublishers.com/jaicm/JAICM.MS.ID.555563.php
Comments
Post a Comment