Juniper Publishers Journal of Anesthesia and Intensive Care Medicine

Juniper Publishers - Journal of Anesthesia Abstract Bleomycin is a drug used to in the treatment of Hodgkin's Lymphoma, amongst other tumours. Bleomycin has been implicated in causing pneumonitis and pulmonary fibrosis, now termed Bleomycin Lung Injury (BLI). BLI is a much debated subject, in terms of both its pathogenesis and management of patients after diagnosis. In this paper, we reviewed the current knowledge of Bleomycin-Induced Lung Injury from a case report perspective. We will describe the case of a patient with BLI presenting to our ICU and discuss the available literature. Keywords: Bleomycin; Acute Lung Injury, Chronic Lung Injury, Pneumonitis, Drug Toxicities, Free radicals Abbreviations: BLI: Bleomycin Lung Injury; ARDS: Acute Respiratory Distress Syndrome; ICU: intensive care unit Introduction Bleomycin is a glycopeptide antibiotic, originally isolated from Streptomyces verticillus, and discovered t...

Juniper Publishers: Approaches for Modeling the Complex Dynamic System... : Robotics & Automation Engineering Journal Nowadays many dynamic systems, both deterministic as well as stochastic by nature, have ...

Juniper Publishers: Stem Cells to Improve the Wound Healing-Juniper Pu... : Journal of Head Neck & Spine Surgery The cellular therapy using Mesenchymal Stem Cells, specially its two subtypes - Bone-marrow M...

Juniper Publishers: Public Health Interventions in Cystic Fibrosis-Jun... : International Journal of Pulmonary & Respiratory Sciences   The United States invests billions of dollars dedicated to funding ...

Juniper Publishers - Journal of Anesthesia Abstract Objectives: Evaluating effect of oral labetalol pre-medication followed by low-dose intraoperative (IO) labetalol infusion on IO heart rate (HR) and mean arterial pressure (MAP), blood loss and need for transfusion and urine output (UOP) of patients undergoing open abdominal myomectomy. Patient & methods: Eighty-eight patients were randomly divided into: Study patients received 200 mg oral labetalol 2-hr before surgery and IO labetalol infusion (0.2mg/kg/hr) till completion of myomectomy. Control patients received placebo infusion and all patients received the same anesthetic protocol. Results: Operative blood loss and transfusion needs were significantly lower, but UOP was significantly higher in study than control patients. Oral labetalol significantly decreased preoperative HR and MAP of study patients compared to their baseline measures and to control patients. Oral labetalol significantly decreased ...

Juniper Publishers - Journal of Anesthesia Abstract Insulinomas are rare tumours that present with recurrent hypoglycaemic episodes. They are often misdiagnosed or diagnosis is often delayed due to their bizarre clinical presentation. Diagnosis of insulinoma is made based on history (Whipple's Triad), biochemical tests and imaging modalities. Treatment includes medical and surgical management. We intend to describe the anaesthetic management of three cases of insulinoma observed over a period of one year and review the existing literature. Though rare, when they do occur, these tumours pose a great challenge to anaesthesiologists. Vigilant monitoring of blood sugars intraoperatively is a must to counteract these wide swings, hence providing a better patient outcome. Keywords: Insulinoma; Anaesthetic management; Hypoglycaemia; Whipple's Triad; Intraoperative ultrasound (IOUS) Introduction Insulinomas are rare t...

Juniper Publishers: Further Developments on the T-Transmuted X Family ... : Biostatistics and Biometrics Open Access Journal   We review the exponentiated generalized (EG) T-X family of distributions and prop...